
OSF Healthcare

While having a predisposition for Alzheimer's is not a diagnosis, it can help someone take the appropriate preventative measures. Hemsworth has said he is going to spend time focusing on stress and sleep management, nutrition and fitness.
According to the Alzheimer's Association, Alzheimer's is the most common cause of dementia, making up 60-80% of dementia cases. Dementia is not a normal part of aging, and is caused by damage to brain cells that can lead to memory problems, confusion and communication issues. "With dementia, it's a short term, memory-deficit, but usually long term is intact," said Andrea Shewalter, a nurse practitioner with OSF HealthCare Illinois Neurological Institute (INI). "People will forget what they ate for breakfast that day and they may forget having a specific conversation with a family member that morning or the day before, but they'll be able to tell you what they did 25 years ago and be able to reminisce with stories like that." Typically it's a loved one who notices the initial troubling signs of dementia such as memory loss, problem-solving difficulties or issues with daily tasks such as paying bills, taking medication or preparing meals, so it's the patients who are accompanied by family members to an appointment who are most likely exhibiting the greatest symptoms of dementia. Shewalter adds that anyone is a candidate for testing. And if you have a loved one who has been diagnosed with dementia you do not need to wait to develop symptoms to look into testing options for yourself. "When patients come in we refer them for a neuro psychological evaluation, where the psychologist reviews the 12 different domains of the brain through different systems and assessments," she says. "And they can come up with a potential diagnosis and are able to tell us what part of the brain is having a deficit or what deficit of the brain is occurring." But arriving at a dementia diagnosis isn't always easy. Physicians have to recognize a pattern of loss of skills and function and determine what a person is still able to do. And it usually takes more than one test to come up with the diagnosis. Tests include cognitive and neuropsychological tests, neurological evaluation, brain scans, lab tests and sometimes psychiatric evaluation. "I would refer anyone for neuropsychological testing, where they can help determine what areas of the brain are being affected," says Shewalter. "And then we usually send the patient for imaging to make sure that there's nothing from a pathological standpoint that's going on in the brain. Is there a brain tumor? Is there Lyme's disease? Is there some sort of disease that is affecting this? We can also look at the structures of the brain to be able to tell if there a lot of shrinkage for their age. Is the brain compensating due to the atrophy or the shrinkage of the brain?"(Family Features) - Although the COVID-19 pandemic turned the world upside down, the rapid development of multiple vaccines has spurred hope that treatments – or even potential cures – may be found for other devastating conditions. One such candidate is Alzheimer’s Disease.
The Alzheimer’s Association defines the disease as a type of dementia that affects memory, thinking and behavior. While some degree of memory loss is common with age, Alzheimer’s symptoms are significant enough to affect a person’s daily life and typically only grow worse over time.
Early signs of Alzheimer’s include trouble remembering new information, solving problems or completing familiar tasks. As the disease progresses, disorientation, confusion, significant memory loss and changes in mood or behavior may become apparent. Physical symptoms may include difficulty speaking, swallowing or walking.
Among people aged 65 and older, 1 in 9 (11.3%) has been diagnosed with Alzheimer’s Disease, meaning more than 6 million Americans live with it. Worldwide, the World Health Organization estimates there are nearly 50 million people living with dementia, and Alzheimer’s likely accounts for 60-70% of those. By 2050, this number could rise as high as 13 million. Less commonly noted are the numbers of early-onset (under 65 years old) Alzheimer’s patients within those figures. Up to 9% of global Alzheimer’s cases are believed to be early onset, according to the World Health Organization.
According to a Harvard School of Public Health survey, Alzheimer’s is second only to cancer among America’s most feared diseases. However, data from the Alzheimer’s Association shows Alzheimer’s is the sixth-leading cause of death in the United States, a rate higher than breast cancer and prostate cancer combined.
Beyond the personal impact for those battling the disease and their loved ones, Alzheimer’s Disease also takes a significant economic toll. The Alzheimer’s Association predicts that in 2021, Alzheimer’s and other dementias will cost the nation $355 billion. By 2050, these costs could exceed $1 trillion if no permanent treatment or cure for Alzheimer’s is found. At the same time, more than 11 million Americans provide unpaid care for people with Alzheimer’s and other dementias, an estimated 15.3 billion hours of care, valued at nearly $257 billion.
While there hasn't been enough significant progress in discovering a treatment or cure in the more than 100 years since Alzheimer’s was first identified in 1906, early diagnosis and treatment may improve the quality of life for patients. The disease affects each patient differently, so therapies vary widely depending on how far it has progressed and which symptoms are most prevalent. Some therapeutic approaches can address symptoms like sleep disruption and behavior while medication may be beneficial for treating other symptoms.
Founded in 2016 by Milton “Todd” Ault III, Alzamend Neuro, a preclinical-stage biopharmaceutical company, has been actively seeking a cure for Alzheimer’s and concentrates on researching and funding novel products for the treatment of neurodegenerative diseases and psychiatric disorders. With two products currently in development, the company aims to bring these potential therapies to market at a reasonable cost as quickly as possible.
Ault’s stepfather is currently battling Alzheimer’s, his mother-in-law died from the disease and he has three other family members suffering through it.
“Even though work has been done to find a cure for Alzheimer’s, to me it hasn’t been a full-court press,” said Ault, whose many personal encounters with Alzheimer’s have further fueled his passion to find a cure. “While there are no profound treatments today for Alzheimer’s disease, we believe we can change that.”
Some basic changes in the approach to disease research could accelerate progress for diseases like Alzheimer’s, said Milton “Todd” Ault III, founder of Alzamend Neuro.
Ault believes recent advancements in vaccines and medical technology, combined with these five approaches, can help advance the search for a cure for Alzheimer’s disease and other dementias.
Encourage public-private partnerships
The collaboration of government agencies and private industries was integral to the COVID-19 vaccine development. The cross-industry partnerships enabled a vaccine to get to market in less than one year despite detractors. Ault believes this model can be replicated for other diseases and conditions.
Because of its complexity, a cure for Alzheimer’s will require expertise from a broad range of organizations including health and defense, biopharmaceutical firms, academic experts and those involved in Operation Warp Speed, the federal effort that supported multiple COVID-19 vaccine candidates simultaneously to expedite development.
Share standards and data
Focusing on a shared goal is vital to succeeding. This means looking for ways to share standards and collaborate with colleagues and competitors regardless of proprietary data, patents and other limitations.
Become the catalyst for a cure
When political will and government funding are insufficient or unable to drive change, the private sector can inspire action.
“The progress we are making is a result of the private investment dollars we secured and the way we have applied strategy and tenacity that comes from a successful business record,” Ault said.
Learning from past successes
Aside from the result, there is a great deal to learn from the successful development of past drugs and vaccines. Social awareness and cultural demand are potential ways to stimulate faster production and approvals between public and private entities.
To learn more about treatments and therapies in development visit alzamend.com .
There are several reasons for learning a second, third or even fourth language. In Europe, with smaller nations and nearly unrestricted travel between them, it is not uncommon for residents to pick up another language or two and be able to communicate effectively. Nearly every country in Europe requires students as young as six to learn a foreign language, usually English, according to The Pew Research Center.
Generally speaking, most high schools in the America offer foreign language classes, but only 15% of our country's elementary schools do the same. Except as a college requirement, there is not national US mandate like in Europe to acquire second language ability.
Sadly, less than one percent of American adults who studied a foreign language are remotely capable of carrying a conversation in that language. It isn't because Americans are dumber - although some might dispute that after the last two presidential election cycles - or less capable, but because the educational system's approach is fundamentally flawed, which is a topic for another time.
I gutted out three years of Spanish in high school and now some 40 years later, I am admittedly not in that one-percent club. I can order a beer in Español and ask where is the nearest bathroom, mostly in that order because that's just how life works. I have always held mad respect for anyone who can speak two or more languages fluently.
While caring for a relative who was suffering Alzheimer's and assessing my own risk in the next 20 or so years, I learned research has shown that people who are bi-or multilingual experience a delay in the onset of symptoms from dementia by 4-5 years when compared with monolingual patients. Why didn't they know that information back when I was struggling in Señor Kruzan's junior-year Spanish class?
Despite incredible resistance to the endeavor and the insistence everyone within our borders speak American, there are dozens of reasons to learn to speak one or more languages. Regardless of whether you want to slow the degeneration of your cognitive ability or want to increase your upward career mobility, here are six practical reasons to learn a new language that make absolute sense.
1. Learning another language stalls the onset of Alzheimer’s & dementia.
While there is no absolute guarantee, multiple studies suggest that degenerative brain diseases like Alzheimer’s and dementia advance at a much slower pace than those how are multilingual. In one published study researchers found a small but significant protection for people who speak more than two languages. However, no significant benefit was seen in those who were bilingual.
2. Learning another language opens opportunities in high paying careers
If you can speak and read in one or more languages in addition to English, there are endless exciting opportunities in government service sector, law enforcement and the military. A woman I know has the perfect pandemic job. She charges $40 an hour tutoring high school and college students in Spanish.
3. Speaking a second or third language comes handy when you want to have a discreet conversation
You are having a great time at Barraca, a dance club in Valencia, Spain, when you meet the next Mr. or Mrs Right - or at least Right Now - and you need to fly solo. No better way to tell them to drop back or peel off than in another language. Oh, and there is no better way to share your displeasure on your boss' latest silly workplace edict with co-workers know or studying the same language.
4. Make new friends from around the world
Learning to communicate in other languages opens the door to meeting interesting people from other parts of the world and forging future personal and business relationships. Best of all when you visiting their city or country, you'll get the inside scoop on where to go and what to do off the well-worn tourist paths for a unique, memorable trip.
5. Improve your memory & cognitive performance
Studies have shown bilingual people have better working memories, superior speed when switching between different tasks and have an easier time learning new things. Like doing bicep curls to build strength, learning a new language strengthens brain functions.
6. Learning a new language is fun
Learning to speak another language is fun, just not so much in a high school and college setting. Unfortunately, both the methodology and process used by the educational system in the US is whacked. What's fun about speaking another language? It's anything from ordering food in that language to the look on the faces of native speakers when they realize you speak their language pretty well. It's moments watching movies and TV shows when you realize you don't need subtitles.